Artichoke Spinach Grilled Cheese

Featured in: Vegetarian & Vegan

This grilled cheese features a luscious blend of cream cheese, mozzarella, Monterey Jack, Parmesan, fresh spinach, and chopped artichokes. Spread on sourdough slices, then browned in butter until perfectly crisp and melty. A quick, easy main you'll want to savor. Great with a simple salad or tomato soup.

Optional add-ins like sun-dried tomatoes or scallions add extra richness. Use whole wheat or gluten-free bread for dietary needs. Prep ahead and enjoy warm.

Updated on Mon, 12 Jan 2026 09:56:00 GMT
Delicious Artichoke Spinach Grilled Cheese, oozing with melted cheese and creamy spinach–artichoke filling. Save to Pinterest
Delicious Artichoke Spinach Grilled Cheese, oozing with melted cheese and creamy spinach–artichoke filling. | krispyrecipes.com

The best ideas happen when you're staring at a container of leftover spinach artichoke dip and wondering if anyone would judge you for eating it straight from the bowl with a spoon. I stood there in my kitchen at 2pm on a Tuesday, dip in one hand, loaf of sourdough in the other, and realized I was about three minutes away from something magical. The first bite confirmed it—sometimes the most inspired cooking comes from pure laziness wrapped in creativity.

I made these for a rainy Sunday lunch when my sister came over, expecting maybe a casual sandwich situation. Instead we both sat in comfortable silence at the counter, wiping melted cheese from our chins, agreeing this was the best decision we'd made all week. She asked for the recipe before she even finished her first half.

Ingredients

  • Fresh spinach: Fresh gives you brighter color and texture, but frozen works perfectly if you squeeze out every drop of water first
  • Artichoke hearts: Canned or jarred both work—just pat them dry so your sandwich bread stays crisp
  • Cream cheese: Soften it completely so it blends into the other cheeses without any lumpy surprises
  • Mozzarella and Monterey Jack: This duo melts beautifully while the Monterey Jack adds a slight sharpness that cuts through the richness
  • Parmesan cheese: Adds that salty, umami punch that makes the filling taste restaurant-quality
  • Sourdough bread: Sturdy enough to hold all that filling and develops the most gorgeous golden crust
  • Garlic: One small clove is all you need—mince it finely so no one gets an overwhelming raw garlic bite
  • Red pepper flakes: Optional but recommended if you like that gentle heat that sneaks up on you

Instructions

Make the filling:
Toss all your cheeses, spinach, artichokes, garlic, and seasonings in a bowl. Mix until it looks like a cohesive spread—taste and adjust the salt if needed.
Assemble the sandwiches:
Spread the mixture generously on four bread slices. Go all the way to the edges but keep it slightly thinner near the crust to prevent oozing. Top with remaining slices.
Butter the bread:
Spread softened butter on the outside of each sandwich. This is what creates that golden, restaurant-style crunch.
Grill to perfection:
Cook in a hot skillet over medium heat, pressing gently with your spatula. Flip when golden—about 3 to 4 minutes per side—until cheese is completely melted.
Let them rest:
Wait one full minute before slicing. This seems impossible but keeps all that molten filling from escaping.
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| krispyrecipes.com

These have become my go-to when I need to feed a crowd without actually hosting a dinner party. People hover around the kitchen, drawn in by the smell of melting cheese and garlic, and suddenly everyone's asking what's for lunch.

Make It Your Own

The base recipe is perfect as-is, but I've found that adding sun-dried tomatoes or chopped scallions transforms it into something entirely new while keeping the same soul. Sometimes I throw in a handful of chopped fresh basil right at the end—it brightens everything up.

The Bread Question

Sourdough is my absolute favorite here because it stands up to all that moisture without falling apart. That said, whole wheat adds a nice nutty flavor and extra fiber, and good gluten-free bread works surprisingly well if that's your life.

What To Serve With

Tomato soup is the classic pairing for a reason—the acidity cuts through all that rich cheese. A crisp green salad with a vinaigrette works beautifully too. Honestly, these are substantial enough to stand alone with some pickles on the side.

  • Classic tomato soup for dunking
  • Simple arugula salad with lemon dressing
  • Just pickles and call it lunch
Crispy sourdough hugging a gooey core of Artichoke Spinach Grilled Cheese, ready to melt in your mouth. Save to Pinterest
Crispy sourdough hugging a gooey core of Artichoke Spinach Grilled Cheese, ready to melt in your mouth. | krispyrecipes.com

Make these on a dreary afternoon when you need something cozy, or serve them at your next casual get-together and watch them disappear in minutes. Either way, you're in for something wonderfully indulgent.

Common Recipe Questions

What type of bread works best for this sandwich?

Sourdough bread is recommended for its sturdy texture and tangy flavor, but whole wheat or gluten-free options work well too.

Can I prepare the filling in advance?

Yes, the filling can be made up to two days ahead and stored in the refrigerator for convenience.

How can I add extra flavor to the filling?

Adding sun-dried tomatoes or chopped scallions provides a flavorful boost that complements the creamy filling.

What’s the best method to achieve a crispy exterior?

Lightly buttering the outside of each sandwich before cooking on a medium-heat skillet ensures a golden, crispy crust.

Is this suitable for a vegetarian diet?

Yes, this dish contains no meat and relies on cheeses and vegetables, making it vegetarian-friendly.

Artichoke Spinach Grilled Cheese

Golden sourdough sandwich filled with creamy spinach and artichoke blend, melted for a savory and satisfying bite.

Prep Duration
15 minutes
Cooking Duration
10 minutes
Overall Time
25 minutes
Created by Mia Harper

Recipe Type Vegetarian & Vegan

Skill Level Easy

Cuisine Type American

Total Portions 4 Serving Size

Dietary Considerations Veggie-Friendly

What You’ll Need

Vegetables

01 1 cup fresh spinach, chopped (or ½ cup frozen, thawed and drained)
02 1 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Dairy

01 4 oz cream cheese, softened
02 ½ cup shredded mozzarella cheese
03 ½ cup shredded Monterey Jack or Swiss cheese
04 ¼ cup grated Parmesan cheese
05 2 tbsp unsalted butter, softened

Bread

01 8 slices sourdough bread

Seasonings

01 ¼ tsp black pepper
02 ⅛ tsp crushed red pepper flakes (optional)
03 Pinch of salt

How to Make It

Step 01

Prepare filling: Combine cream cheese, mozzarella, Monterey Jack or Swiss, Parmesan, spinach, artichokes, garlic, black pepper, red pepper flakes, and salt in a mixing bowl. Mix until fully incorporated.

Step 02

Assemble sandwiches: Arrange sourdough slices on a flat surface. Evenly spread the spinach-artichoke mixture onto 4 slices, then top each with remaining bread slices to form sandwiches.

Step 03

Butter sandwiches: Lightly spread softened butter on the exterior sides of each sandwich.

Step 04

Cook sandwiches: Heat a skillet or griddle over medium heat. Place sandwiches in the pan, cook for 3 to 4 minutes per side while pressing gently, until bread is golden and cheese melted.

Step 05

Rest and serve: Remove sandwiches from heat, allow to rest for 1 minute. Slice and serve warm.

Tools You’ll Need

  • Mixing bowl
  • Spoon or spatula
  • Knife and cutting board
  • Skillet or griddle
  • Spatula for flipping

Possible Allergens

Double-check each ingredient for allergens and consult an expert if you're unsure.
  • Contains dairy (cheese, butter) and wheat (bread).
  • May contain soy depending on brand.
  • Check ingredient labels for cross-contamination if allergic.

Nutritional Information (per serving)

This data is for informational purposes and shouldn't replace professional advice.
  • Calorie Count: 410
  • Total Fat: 23 grams
  • Total Carbohydrates: 38 grams
  • Protein Content: 15 grams