Zesty Cajun Garlic Parmesan Chicken

Featured in: Quick & Easy Meals

Savor bold flavors in this easy American-Italian fusion featuring juicy chicken, cheese-filled tortellini, and a rich Cajun garlic Parmesan sauce. Quick to prepare, this dish blends the warmth of Cajun spices with creamy dairy notes, fresh aromatics, and a hint of zest from bell peppers. Each bite delivers tender chicken and pasta wrapped in smooth, savory sauce. Pair with crisp white wine or crusty bread for a satisfying dinner. Adjust spice level to taste and garnish with parsley and extra Parmesan for added flair.

Updated on Sat, 08 Nov 2025 09:11:00 GMT
Tender Zesty Cajun Garlic Parmesan Chicken Tortellini in creamy sauce with fresh parsley. Save to Pinterest
Tender Zesty Cajun Garlic Parmesan Chicken Tortellini in creamy sauce with fresh parsley. | krispyrecipes.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I made this dish on a hectic Tuesday evening and was amazed at how the kick of Cajun spice blended perfectly with the creamy sauce and cheesy tortellini, making everyone at the table ask for seconds.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz) refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g) freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped (for garnish)
  • Optional Parmesan: Extra grated for serving

Instructions

Cook tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Brown chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5-7 minutes. Remove chicken from skillet and set aside.
Sauté vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3-4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Make sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add cheese:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Heat through:
Cook for an additional 2-3 minutes until heated through.
Serve:
Serve garnished with fresh parsley and extra Parmesan if desired.
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| krispyrecipes.com

This meal became an instant family favorite, and my kids now request it whenever they want something creamy with a little spicy flair.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons

Allergen Information

This recipe contains wheat, milk, and eggs. Always verify tortellini packaging for specific allergens.

Nutritional Information

Each serving contains about 620 calories, 29 g fat, 53 g carbohydrates, and 38 g protein.

Savor the rich Zesty Cajun Garlic Parmesan Chicken Tortellini, perfect for weeknight dinners. Save to Pinterest
Savor the rich Zesty Cajun Garlic Parmesan Chicken Tortellini, perfect for weeknight dinners. | krispyrecipes.com

This bright and lively pasta is sure to wow everyone at your table. Enjoy every flavorful bite and don&t forget extra Parmesan!

Common Recipe Questions

Can shrimp be used instead of chicken?

Yes, substitute peeled and deveined shrimp for chicken. Sauté briefly until pink, then follow remaining steps as directed.

How spicy is the Cajun sauce?

The Cajun seasoning adds a gentle heat. Adjust with extra red pepper flakes or cayenne for more spice, or reduce for milder flavor.

Can this be made ahead?

Prepare components in advance and assemble just before serving for the freshest texture and flavor. Store sauce and pasta separately if not served immediately.

What wine pairs best with this dish?

A crisp white wine like Sauvignon Blanc or Pinot Grigio complements the creamy sauce and spices nicely.

Is it possible to make it vegetarian?

Omit chicken and add more vegetables, or use plant-based protein alternatives for a vegetarian-friendly version.

Zesty Cajun Garlic Parmesan Chicken

Creamy Cajun Parmesan sauce envelops chicken and cheese tortellini for a flavorful fusion meal.

Prep Duration
15 minutes
Cooking Duration
25 minutes
Overall Time
40 minutes
Created by Mia Harper

Recipe Type Quick & Easy Meals

Skill Level Easy

Cuisine Type American/Italian Fusion

Total Portions 4 Serving Size

Dietary Considerations None specified

What You’ll Need

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley, for garnish
03 Extra grated Parmesan for serving, optional

How to Make It

Step 01

Cook Tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package directions until tender. Drain and set aside.

Step 02

Sauté Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces and season with half the Cajun seasoning, salt, and black pepper. Sauté until browned and fully cooked, approximately 5 to 7 minutes. Remove chicken from skillet and set aside.

Step 03

Sauté Vegetables: In the same skillet, add the remaining olive oil and unsalted butter. Sauté diced onion and bell pepper for 3 to 4 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.

Step 04

Prepare Sauce: Sprinkle in the remaining Cajun seasoning and smoked paprika, then stir to combine. Gently pour in heavy cream and bring the mixture to a simmer, stirring frequently.

Step 05

Finish Sauce: Add grated Parmesan cheese and stir until the cheese melts and the sauce is smooth. Taste and adjust seasoning if necessary.

Step 06

Combine Chicken and Pasta: Return cooked chicken to the skillet along with drained tortellini. Toss gently to coat everything in the creamy sauce.

Step 07

Heat Through: Cook the mixture for an additional 2 to 3 minutes, stirring gently, until heated through.

Step 08

Garnish and Serve: Serve immediately, garnished with chopped fresh parsley and additional Parmesan cheese if desired.

Tools You’ll Need

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Possible Allergens

Double-check each ingredient for allergens and consult an expert if you're unsure.
  • Contains wheat from tortellini
  • Contains milk from cream, Parmesan, and butter
  • Contains eggs in some tortellini varieties

Nutritional Information (per serving)

This data is for informational purposes and shouldn't replace professional advice.
  • Calorie Count: 620
  • Total Fat: 29 grams
  • Total Carbohydrates: 53 grams
  • Protein Content: 38 grams