01 - Preheat oven to 350°F (175°C).
02 - In a skillet over medium heat, cook ground beef with salt, pepper, garlic powder, and onion powder until browned and fully cooked. Drain excess fat.
03 - Slice the slider buns in half horizontally (keep tops and bottoms connected if possible). Place the bottom halves in a greased 9×13-inch baking dish.
04 - Spread the cooked beef evenly over the bottom buns.
05 - Layer the cheese slices over the beef.
06 - Add any optional toppings like caramelized onions.
07 - Place the top halves of the buns over the cheese and beef.
08 - Brush the tops with melted butter and sprinkle with sesame seeds if using.
09 - Cover with foil and bake for 10 minutes. Remove foil and bake for another 5-7 minutes until cheese is melted and buns are golden.
10 - Slice into individual sliders and serve warm.